Friday, December 18, 2009

European Stroke Conference XIX. European Stroke Conference
Barcelona, Spain
25 - 28 May 2010


we are pleased to inform you about the following topics:

1. ESC 2010 Barcelona
2. Call for Papers

1.

ESC 2010 will take place in Barcelona, Spain from 25 – 28 May 2010. Registration for this conference will be available by the end of December 2010. For further information please visit www.eurostroke.eu or contact us by e-mail: esc@congrex.com

2.

All participants (physicians, nurses, AHP) are invited to submit abstracts on one of the topics listed on the website for presentation at the ESC 2010.
There are 2 different submission pages, one each for physicians and nurses/AHP.
In order to standardise the abstract layout, we kindly ask you to read the guidelines on the website carefully.

Abstract submission deadlines:

  • Regular abstract deadline: 17 January 2010

  • Nurses/AHP abstract deadline: 19 March 2010

  • "Ongoing Trials" abstract deadline: 15 May 2010

We hope the content of this e-mail was valuable to you.

With kind regards

European Stroke Conference Administrative Secretariat

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2010 years european stroke conference

Thursday, December 17, 2009

The R User Conference 2010
July 20-23
National Institute of Standards and Technology (NIST),
Gaithersburg, Maryland, USA


Host:

National Institute of Standards and Technology

Sponsors:

R Foundation for Statistical Computing R Logo

About the Conference

useR! 2010, the R user conference, will take place at the Gaithersburg, Maryland, USA campus of the National Institute of Standards and Technology (NIST) from 2010-07-21 to 2010-07-23. Pre-conference tutorials will take place on July 20.

The conference is organized by NIST and funded by the R Foundation for Statistical Computing.

Following the successful useR! 2004, useR! 2006, useR! 2007, user! 2008, and useR! 2009, conferences, the conference is focused on:

  1. R as the `lingua franca' of data analysis and statistical computing,
  2. providing a platform for R users to discuss and exchange ideas how R can be used to do statistical computations, data analysis, visualization and exciting applications in various fields,
  3. giving an overview of the new features of the rapidly evolving R project.

As for the predecessor conferences, the program consists of two parts:

  1. invited lectures discussing new R developments and exciting applications of R,
  2. user-contributed presentations reflecting the wide range of fields in which R is used to analyze data.

A major goal of the useR! conference is to bring users from various fields together and provide a platform for discussion and exchange of ideas: both in the formal framework of presentations as well as in the informal part of the conference in Gaithersburg.

Prior to the conference, on 2010-07-20, there are tutorials offered at the conference site. Each tutorial has a length of 3 hours and takes place either in the morning or afternoon.

Invited speakers:

Mark Handcock, Frank Harrell Jr, Friedrich Leisch, Michael Meyer, Richard Stallman, Luke Tierney, Diethelm Würtz

Program committee:

Louis Bajuk-Yorgan, Dirk Eddelbuettel, John Fox, Virgilio Gómez-Rubio, Richard Heiberger, Torsten Hothorn, Aaron King, Jan de Leeuw, Nicholas Lewin-Koh, Andy Liaw, Uwe Ligges, Martin Mächler, Katharine Mullen, Heather Turner, Ravi Varadhan, H. D. Vinod, John Verzani, Alan Zaslavsky, Achim Zeileis

Organizing Committee:

Kevin Coakley, Nathan Dodder, David Gil, William Guthrie, Olivia Lau, Walter Liggett, John Lu, Katharine Mullen, Jonathon Phillips, Antonio Possolo, Daniel Samarov, Ravi Varadhan

Call for Papers:

We invite all R users to submit abstracts presenting innovations or exciting applications of R on topics such as:

  • Applied Statistics & Biostatistics
  • Bayesian Statistics
  • Bioinformatics
  • Chemometrics and Computational Physics
  • Data Mining
  • Econometrics & Finance
  • Environmetrics & Ecological Modeling
  • High Performance Computing
  • Machine Learning
  • Marketing & Business Analytics
  • Psychometrics
  • Robust Statistics
  • Social network analysis
  • Spatial Statistics
  • Statistics in the Social and Political Sciences
  • Teaching
  • Visualization & Graphics
  • and many more.
To submit an abstract, generate a pdf file using a template (preferred) for pdfTeX or for OpenOffice Writer and commercial friends, or generate a plain txt file. Submit the file via the abstract submission interface. Please keep abstracts to one page.

The abstracts will be available in an online collection in a single pdf file.

Deadline for submission of abstracts: March 1, 2010.

Timeline of the Conference


The scientific program of the conference will start the morning of Wednesday, July 21, and end in the afternoon on Friday, July 23. Prior to the conference, on Tuesday, July 20, several half-day tutorials will be held.

Funding


The Statistical Engineering Division of NIST has generously contributed funding to support those who otherwise would be unable to attend.

As in years past, limited funding from the National Science Foundation (NSF) will also be available for graduate students and junior faculty at U.S. post-secondary institutions.

Instructions regarding applying for support will be posted here on or about January 1, 2010.

Sponsorship


Potential sponsors of the conference can find more information here.

Accommodation


Information regarding accomodation near NIST is here.

About NIST


The NIST webpage links to information about the institute. Also note that there is a NIST YouTube channel.

Travel


Information regarding traveling to NIST is here.

useR_logo

useR! 2010: Tutorials


Before the official program, half-day tutorials will be offered on Tuesday, July 20th.

Morning

Afternoon

Tuesday, December 01, 2009


Call for Abstracts!

Plan now to submit a competitive abstract for a poster or platform presentation for ACTRIMS 2010. The abstract submission site opens December 4.

Session Topics for the Saturday, June 5 meeting include

• Cell Replacement and Repair
• Risk Management
• Complications of Potent Immunosuppressive Agents in MS
• Basic and Clinical Issues in Multiple Sclerosis

Young Researcher Awards
Travel awards and two $1,500 prizes for best platform or best poster presentation are available to presenters 35 years old or younger, i.e., born on or after January 1, 1975.


This activity has been approved for AMA PRA Category 1 CreditTM.

The 15th annual ACTRIMS meeting is jointly sponsored by the University of Maryland School of Medicine and ACTRIMS.


Organizational support for ACTRIMS meetings is provided by the National Multiple Sclerosis Society in collaboration with the MS Society of Canada.

From:
Research & Clinical Programs Department
National Multiple Sclerosis Society
733 Third Avenue
New York, NY 10017 USA
212-476-0469

Tuesday, November 24, 2009

Postdoctoral Fellowship Opportunity, PhD/or MD, Molecular Imaging

UCLA SOMI

The UCLA Scholars in Oncologic Molecular Imaging (SOMI) Program is a unique postdoctoral training program for biological researchers and physicians who desire to integrate molecular imaging and cancer research. Molecular imaging provides powerful and sensitive tools to observe and measure the molecules, molecular processes, and events that distinguish malignant from normal tissues. Oncologic molecular imaging combines the disciplines of cellular and molecular biology, chemistry, physics, biomathematics and bioinformatics, pharmacology, imaging sciences, and clinical medicine to advance cancer research, diagnosis, and management.

Postdoctoral fellows, with backgrounds from across the basic sciences and medicine, will participate in an integrated, cross-disciplinary training program under the mentorship of a diverse group of basic science and clinical faculty members representing 7 departments and 6 divisions in the David Geffen School of Medicine, the College of Letters and Sciences, and the Henry Samueli School of Engineering and Applied Science. The centerpiece of the program is the opportunity to conduct innovative molecular imaging research co-mentored by two faculty members from complementary disciplines. Fellows also engage in specialized coursework, seminars, and a clinical tutorial program. Graduates of SOMI will be uniquely trained to lead research programs to study cancer in an organismal context with state-of-the-art technologies.

Support is provided for salary, supplies and travel, for up to three years. Applicants must hold a Ph.D. or M.D. degree and must be either a US citizen or permanent resident. Minority candidates are encouraged to apply.

Contact:

Erika Corrin
Crump Institute for Molecular Imaging
UCLA
570 Westwood Plaza
Los Angeles, CA 90095-1770
campus mail code: 177010
phone: (310) 825-4903
fax: (310) 206-8975
email: ecorrin@mednet.ucla.edu

Tuesday, November 17, 2009

ECTRIMS Research Fellowship Exchange Programme

Deadline 1 December 2009

Dear Doctor

ECTRIMS is pleased to announce its Research Fellowship Exchange Programme competition for the coming year.

The fellowship is offered to young European postdoctoral neuroscientists (MD, PhD, ScD or equivalent) to facilitate their conduct of and training in basic, clinical or applied research related to MS in European laboratories or clinics. The goal is to maximize exchange of information and help grow the pool of well-trained scientists focused on MS.

ECTRIMS will support up to two fellowships annually, each with duration of 1 or 2 years, with an annual stipend of up to €40,000 - €50,000, depending on the candidate’s degree. Fellows are expected to identify a European research training environment and mentor prior to application and to devote full-time to research and research training during their fellowship period (up to 10% time and effort can be spent on teaching and/or clinical care).

Details about the ECTRIMS Research Exchange Fellowship Programme and application materials can be obtained from the ECTRIMS web site:

www.ectrims.eu

or by writing to the ECTRIMS Fellowship Administrator at:

fellowship@ectrims.eu

With kind regards

ECTRIMS Fellowship Administration
c/o Congrex Switzerland Ltd.

The Hellman Fellowship in Science and Technology Policy
AAAS Hellman Fellowship

The Hellman Fellowship in Science and Technology Policy is intended for early-career professionals with training in science or engineering who are interested in transitioning to a career in public policy and administration. While in residence, the Hellman Fellows work with senior scientists and policy experts on critical national and international policy issues related to science, engineering, and technology.

Hellman Fellows work on one or more of the projects under the Academy’s Initiative for Science, Engineering, and Technology (see below). The mission of the Initiative is to examine, in broad terms, how the world of science and technology is evolving, how to help the public understand these changes, and how society can better adapt. The Initiative brings together scientists and public policy experts in a neutral setting, outside of the constraints of the political process.

MEET THE HELLMAN FELLOWS

The overall objectives of the Hellman Fellowship Program are as follows:

To provide a setting and resources for an early-career professional to develop expertise on issues of science, engineering and technology policy;
To increase the cadre of young science-policy professionals who are engaged in substantive discussion of science and engineering research questions with a broad understanding of their social implications; and
To increase the scale of American Academy projects and studies on science, engineering, and technology.

Fellowship Eligibility: Applicants must have a Ph.D. in an area of science or engineering and have some experience or a demonstrated interest in an area related to science and technology policy. Masters degrees may be considered in the fields of engineering and computer science. Strong writing and organizational skills are desired. Candidates must be U.S. citizens or permanent residents.

About the American Academy: Founded in 1780, the American Academy of Arts and Sciences is an independent policy research center that conducts multidisciplinary studies of complex and emerging problems. The Academy’s elected members are leaders in the academic disciplines, the arts, business, and public affairs.

With a current membership of 4,000 American Fellows and 600 Foreign Honorary Members, the Academy has four major goals:

Promoting service and study through analysis of critical social and intellectual issues and the development of practical policy alternatives;
Fostering public engagement and the exchange of ideas with meetings, conferences, and symposia bringing diverse perspectives to the examination of issues of common concern;
Mentoring a new generation of scholars and thinkers through the Visiting Scholars Program; and
Honoring excellence by electing to membership men and women in a broad range of disciplines and professions.

The Academy's main headquarters is in Cambridge, Massachusetts. With its geographically diverse membership, it has active programming around the United States and abroad.

Terms: Appointments are for a one-year term (with a possibility of renewal) to begin in September at the American Academy in Cambridge, Massachusetts. Stipends are competitive and commensurate with experience. Application: Send a cover letter indicating interest in and experience related to one or more of the topics listed below, curriculum vitae, and 3 letters of reference by January 15, 2010 to:

By Email: hellmanfellow@amacad.org

By Regular Mail:
Hellman Fellowship Program
American Academy of Arts and Sciences
136 Irving Street Cambridge, MA 02138

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Initiative for Science, Engineering, and Technology Projects:

Alternative Models for the Federal Funding of Science and Their Potential to Nurture the Next Generation of Scientists. This study group examines current funding policies, mechanisms, and processes, and strategies for maximizing the impact of science funding. The study considers, for example, the effects of boom and bust funding cycles, the proper balance of capacity-building versus merit in funding considerations, the proportion of funds set aside for high-risk versus incremental research, and whether the current system of distributing funds is effective in supporting and retaining early-career scientists.
Scientists’ Understanding of the Public. Public attitudes about science and technology are complex, informed by a variety of sources, anchored by ethical considerations, religious beliefs, and cultural norms and values. In certain fields—for example, nuclear research, genetic engineering, research on dangerous pathogens, and nanotechnology—scientific progress and public policy concerns may come into conflict. The capacity of scientists to gain adequate funding for their work and to provide sound advice to policy makers depends crucially on their understanding of the social implications and likely public responses to their research. The project convenes scientists to discuss means of addressing this problem.
Science and the Liberal Arts Curriculum. The Academy is undertaking a study to examine the role of science education in the liberal arts curriculum. More than two-thirds of enrolled students at colleges and universities do not major in the natural sciences, engineering, or mathematics. For these students, the science courses they take in college represent their last formal science education. The primary objectives of the study are to: 1) examine philosophies behind science requirements for nonscientists in the liberal arts curriculum, 2) determine how non-science majors fulfill their science requirements, and 3) disseminate findings to enrich discussions of curriculum reform at higher education institutions.
Global Nuclear Future. The objective of the project is to provide a comprehensive evaluation of ways in which present trends—toward more widely distributed nuclear power, more nuclear weapons, more nuclear-weapon-states, and less arms control and international regulation of the world’s nuclear affairs—can be deflected to reduce the likelihood of conflict involving fissile materials. The project is addressing issues such as managing the nuclear fuel cycle, improving nuclear safety and security, US nuclear weapons policy, and challenges of disarmament.
Securing the Internet as Public Space. This study examines the social, political, economic, and legal bases of Internet security. The fundamental social building blocks of Internet communication—i.e., trust, power and control, and identity—are mediated by the technical protocols that underlie the Internet’s basic operation. By bringing together perspectives on both the social and technical requirements for Internet security, the project will offer recommendations for effective policies and design choices.

Saturday, November 14, 2009

Sci Transl Med 28 October 2009:
Vol. 1, Issue 4, p. 4ec14
DOI: 10.1126/scitranslmed.3000515
  • Editors' Choice

Exquisitely Sensitive Imaging

  1. Kelly LaMarco

+ Author Affiliations

  1. Science Translational Medicine, AAAS, Washington, DC 20005, USA

Blood vessels take center stage in sundry disease states, such as stroke and tumor metastasis. But currently available imaging methods like ultrasound, magnetic resonance imaging, positron emission tomography, and fluorescence microscopy, either are unable to resolve individual capillaries or necessitate the use of contrast materials to enhance resolution. Fluorescence is generally a powerful imaging method, but it relies on the tendency of molecules to emit light on their own when they're excited, and the components of blood don't cooperate. Now, Min et al. describe a method that employs stimulated emission in place of fluorescence. In this technique (which underlies the operation of lasers), excited molecules are given a push by a light beam, causing them to emit more light than they would otherwise. The authors exploit stimulated emission to achieve sensitive detection of light-absorbing moieties in biologically important molecules with undetectable fluorescence, such as hemoglobin. Indeed, they were able to visualize individual red blood cells within single capillaries. The authors anticipate that their method will reveal the three-dimensional distribution of oxygen in blood, a measure that will be valuable when interrogating a variety of disease states. They also suggest that the cost of the sophisticated instruments required for this method will be lowered if fiber lasers are adapted for use in this context.

W. Min et al., Imaging chromophores with undetectable fluorescence by stimulated emission microscopy. Nature 461, 1105–1109 (2009). [Abstract]

Friday, October 30, 2009

NIH-Oxford-Cambridge Biomedical Scholars Program

Dear Colleague,

We would like to bring to your attention to the NIH-Oxford-Cambridge Biomedical Scholars Program, an interdisciplinary, accelerated training program with some innovative features that may appeal to your top students. Since 2001, scientists at NIH have collaborated with colleagues in Oxford and Cambridge to create a partnership PhD training program spanning the full breadth of research in these institutions. Every student admitted to the program is fully funded for the length of training.

When compared with traditional U.S. PhD programs, the NIH-Oxford-Cambridge partnership is designed to significantly reduce the time it takes to earn the doctoral degree. Our partnership students generally earn their degrees in four years, and graduates are easily obtaining excellent post-doc positions, faculty appointments, and positions with biotech companies, to name a few of the opportunities awaiting these highly qualified individuals.

As we work to recruit the Class of 2010, we will be searching for highly self-directed students with significant research experience who are ready to focus on a particular dimension of biomedical research in their chosen fields of study. Each year, we receive applications from the nation’s top science students. Additionally, the NIH has cultivated agreements with the Rhodes Trust, the Marshall Commission, and the Churchill and Gates Cambridge scholarships, enabling these talented scholars to extend their master’s degree programs into a PhD with a U.S. lab component. The program is also compatible with the NIH MD/PhD Partnership Training Program, which offers funding for combined M.D./Ph.D. training in collaboration with over twenty U.S. medical schools participating in the Medical Scientist Training Program (MSTP). We have admitted numerous HHMI Scholars into the M.D./Ph.D. Program via the program’s Track 2 admissions pathway. For details about the M.D./Ph.D. options and training tracks, please consult http://gpp.nih.gov/Prospective/InstitutionalPartnerships/MSTPatNIH/ .

Students admitted to the program choose a research project from a pre-existing list of collaborations (see our web site for the list) or are free to design their own project, often bridging different disciplines. They write a detailed research proposal during their first summer in the program and begin their thesis research immediately. We require that Scholars spend two years at the NIH and two years in the UK, working in the labs of their chosen mentors. They earn the doctoral degree from whichever UK institution they select for their doctoral work.

The application deadline for 2010 is January 4th, so please forward the email below and enclosed flyers to interested students. We would also greatly appreciate it if you would post the flyers at appropriate locations on campus.

If you have any questions, do not hesitate to contact me. More information can be found at the program website (http://oxcam.gpp.nih.gov)

-------------------------------------------------------------------------------------------------------------------

Dear Prospective Student,

I am writing to tell you about a groundbreaking biomedical research doctoral program—the National Institutes of Health-Oxford-Cambridge Scholars Program. This innovative program grew from the realization that the next generation of research scientists will increasingly need to adopt interdisciplinary approaches as they strive to produce high impact research outcomes whether basic or clinical.

This is an accelerated program, and students typically receive a doctoral degree in approximately four years. There is no standard curriculum or required coursework. Rather, each student pursues an individualized course of study in which thesis work is initiated at the beginning of the first year. The thesis project is carried out as a collaboration between two labs, with half the research undertaken at NIH and half at one of the UK universities and each student being mentored by a senior scientist at each location. The program takes advantage of the superb resources and training environments at Oxford, Cambridge, and the NIH, the world’s largest biomedical research facility, the main campus of which is located in Bethesda, Maryland where a diverse community of scientists conduct their research in over 1000 laboratories and the world’s largest clinical research center conducts more than 1000 clinical research protocols.

>From its first class that matriculated in 2001, NIH-Oxford-Cambridge Scholars have achieved at the highest levels of biomedical research, publishing first-author papers in journals such as Nature, Nature Medicine, Nature Immunology, Proceedings of the National Academy of Sciences, and The Journal of Experimental Medicine. Graduates have gone on to do post-doctoral training in top academic institutions and industry labs, and a few have gone directly to faculty positions.

All students are fully funded by the NIH for the duration of their doctoral work at both research sites and receive a stipend, health insurance, and travel assistance. Through the NIH M.D./Ph.D Partnership Training Program, we also offer funding for combined M.D./Ph.D. training in collaboration with over twenty U.S. medical schools participating in the Medical Scientist Training Program (MSTP). This option may be of interest to those of you already enrolled in medical school point or applying to traditional MD/PhD programs this year. For details about the M.D./Ph.D. options and training tracks please consult http://gpp.nih.gov/Prospective/InstitutionalPartnerships/MSTPatNIH/ .

The application deadline for Ph.D. and M.D./Ph.D. candidates is January 4th, 2010. The free application is available online through the program website at http://oxcam.gpp.nih.gov via the “Apply Now” button. On our web site you will find additional program details, FAQs, student biographies, descriptions of some of the exciting research projects underway, and more. We would also like to invite you to participate in a teleconference call to learn more about our programs. Please email us at oxcam@mail.nih.gov or mdphd@mail.nih.gov if you would like more information or would like to participate in a conference call.


Please take a look at the flyers through the links below and feel free to contact me if you have any questions. We hope to hear from you soon!

http://oxcam.gpp.nih.gov/prospectiveStudents/documents/OXCAM2010Flyerwdeadline.pdf
http://oxcam.gpp.nih.gov/prospectiveStudents/documents/MSTPflyer2010.pdf

All the best,


Michael Lenardo, M.D.

Program Director

NIH-Oxford Cambridge Scholars Program


Richard Siegel, M.D., Ph.D.

Program Director

NIH M.D./Ph.D. Partnership Training Program

Bridget Lampert, M.S. Ed

Managing Director
NIH-Oxford-Cambridge Scholars Program
NIH M.D./Ph.D. Partnership Training Program
(301) 496-6083

Thursday, October 22, 2009

7th BI-ANNUAL

2009 MINNESOTA WORKSHOPS

on

HIGH FIELD MR IMAGING AND SPECTROSCOPY

and MR IMAGING of BRAIN FUNCTION

OCTOBER 9-11, 2009

http://www.cmrr.umn.edu/workshops/Workshop_09/


CONFERENCE GOALS

The goal is to provide a forum to introduce and discuss the technical issues and applications of MRI/MRS conducted with high magnetic fields (>= 3 T). Presentations from experts in the major areas of high field MR research will discuss fundamental principles, methodology, and applications. After attending this workshop, individuals can expect to be well informed of the advantages and limitations of high field MR and will have acquired much of the basic knowledge necessary to undertake high field MR investigations.

Functional magnetic resonance imaging (fMRI) has evolved into a widely used method for studying brain function and high magnetic fields continue to play an important role in obtaining improved functional maps. By bringing a group of recognized experts who are in the forefront of the field, this workshop will provide an in-depth overview of fMRI, including basic principles, underlying physiology, new developments and various applications. Designed as both an educational program and a scientific forum for the presentation of the state-of-the-art research, the workshop is intended for a wide spectrum of basic and clinical scientists including cognitive scientists, physicists, radiologists, neurologists, neuropsychologists, psychiatrists and others interested in the technical development and applications of fMRI.

TRAINING WORKSHOPS

The training courses are designed to provide attendees with hands-on experience. The courses are mainly targeted for individuals who are new to the field. Attendees participate in lab sessions designed to illustrate each topic covered in lectures. For trainees that will also attend the workshop, lectures are scheduled to provide an overview of the topics covered by workshop speakers.

fMRI TRAINING COURSE

Hands-on Training, October 6-8, 2009

fMRI Data Acquisition
  1. Block-design fMRI data collection
  2. Event-related experiments
  3. Perfusion contrast
  4. fMRI Data Processing
  5. Data pre-processing
  6. General Linear Model and Model-Free analyses
  7. Analysis in commercially available packages

MULTI-CHANNEL TRANSMIT B1 MANIUPULATION AT HIGH

Hands-on Training, October 7-8, 2009

The following topics will be covered in lectures (morning sessions) and in-vivo demonstration at the scanner (afternoon sessions):

  1. Fast multi-channel B1 mapping
  2. Static B1 shim in small targets
  3. Static B1 shim in large targets
  4. Excitation k-space trajectories measurement
  5. B1 homogenization within an axial slice ("spoke excitation k-space trajectories")
  6. 2D parallel excitation ("Transmit SENSE")

A human 7 T Siemens system capable of static B1 shim on 16 channels (one transmitter RF shaping board) will be used to demonstrate topics 1, 2 and 3.

A human 9.4 T Varian system capable of independent parallel transmission on 8 channels (8 transmitter RF shaping boards) will be used to demonstrate topics 4, 5, and 6.

SPECTROSCOPY TRAINING COURSE Hands-on Training, October 7-8, 2009

The following topics will be covered in lectures, hands-on sessions, and demonstrations:

  1. pulse sequences
  2. shimming
  3. data acquisition using Varian and Siemens scanners
  4. processing
  5. data analysis focusing on using LCModel

POSTER PRESENTATIONS

Limited number of posters will be accepted for presentation, and the authors of selected posters will be additionally provided with an opportunity to give a short oral presentation. If you would like to present a poster at the workshop, please submit a one-page abstract via e-mail to deb@cmrr.umn.edu or mail to Deb Morgan, CMRR, 2021 6th ST SE, Minneapolis, MN 55455. The abstract must be received by September 1, 2009.

fMRI TRAINING COURSE

OCTOBER 6-8, 2009

SPECTROSCOPY TRAINING COURSE

OCTOBER 7-8, 2009

MULTI-CHANNEL TRANSMIT B1 MAINIPULATION AT HIGH FIELD TRAINING COURSE

OCTOBER 7-8, 2009

CANMRDG Program
2009 Meeting
Saturday, November 7, 2009
Baxter International Inc., Deerfield, IL
http://www.chem.purdue.edu/canmrdg/

Dear NMR Colleagues,

This year’s final program for the CANMRDG on November 7 at the Baxter Campus in Deerfield Illinois is now posted on our website http://www.chem.purdue.edu/canmrdg/.
The meeting will be held in the Conference Center and begins at 8:15 am (The first Saturday on Central Standard Time!). Please note that prior Registration is required to enter the Baxter Campus. Directions, parking and hotel information are available as links on the website.

Once again we are delighted to welcome two outstanding NMR scientists as our keynote speakers:- Professor Cindy Larive (University of California Riverside) and Professor Jim Prestegard (University of Georgia; Director of the Complex Carbohydrate Research Center). In addition, we have had an overwhelming number of papers submitted by our community and this has produced a very full program – please note we will start at 8:15 and run until 5:30 with cooperation from the speakers.

Please thank our faithful sponsors for their continued support for the meeting – Bruker, Cambridge Isotopes Lab, ISOTEC-Sigma-Aldrich, Protasis, and Varian. Links to our sponsors’ web-sites are found on our home page. Without their support we could not hear from our fine keynote speakers.
A very special thank-you is also due to Joe Ray and Christina Szabo and the staff at Baxter for all their support and efforts in arranging the meeting details, and finding speakers. They have done a superb job.
Your attention is called to the following items so that the meeting can run smoothly.

1.Registration: The registration form on the web MUST be completed by Friday, October 30. for admission to the Baxter site. Their Security Guards require a list of attendees in advance. It will also assist the folks at Baxter to plan the meeting space and breaks.

2.Lunch: We will have a buffet style lunch on the Baxter site this year. The price is $20 per person. A special discount rate of $10 per person is available for students courtesy of a generous donation by a sponsor. Advance registration for lunch is essential for catering purposes. Please click the “Yes” button on the registration form on our website by Noon Friday, October 30 to guarantee your lunch. The lunch list will be updated each day on the CANMRDG web site between 4:30 and 5:00pm so you can check your lunch status. No registration means no food! Once again no shows will be requested to pay for unused meals.

3.Maps, Lodging & Parking Information: These can be found under the links on the web-site http://www.chem.purdue.edu/canmrdg/.

I look forward to seeing you on November 7. Don’t forget to register on the web by Oct 30
Any questions or comments, please feel free to contact me by email at grutzner@purdue.edu or call 765-494-5247 (afternoons).
Last-minute details and information regarding the Baxter site can be provided by Christina Szabo, christina_szabo@baxter.com.

Yours resonantly,
John B. Grutzner

Meeting Program

Chair: John Grutzner (Purdue University)
8:15 ‐ 8:30 Welcome: Norbert Riedel (Chief Scientific Officer, Baxter)
8:30 ‐ 8:50 Progress Toward Automatic Structure Verification Assisted by
Connectivity in Dual Microcoil NMR Ke Ruan (Pfizer Inc.)
8:50 ‐ 9:10 rNMR - Open Source Software for NMR Data Analysis
Seth Schommer (University of Wisconsin Madison)
9:10 ‐ 9:30 Universal Quantitations by NMR: Solvent Concentration Reference
and Receiving Efficiency Hauping Mo (Purdue University)
9:30 ‐ 9:50 Photodimerization of A-Trans-Cinnamic Acid: Domain Sizes in Irradiated
Single Crystals Sarah Mattler (Washington University St. Louis)
9:50 ‐ 10:05 Contribution of Long-Range Interactions to the Secondary Structure
of an Unfolded Globin Daria Fedyukina (University of Wisconsin Madison)
10:05 Coffee
Chair: Christina Szabo (Baxter)
10:30 ‐ 10:50 The Use of In Vitro Chemoselective Isotopic Tagging to Enhance
NMR-Based Metabolic Profiling Tao Ye (Purdue University)
10:50 ‐ 11:10 Global Metabolomics of Breast Cancer Cells Quincy Teng (US EPA)
11:10 ‐ 12:10 Keynote Lecture: Adventures in Mixture Analysis by NMR
Cynthia Larive (University of California Riverside)
12:15 Lunch
Chair: Joe Ray (Baxter)
1:30 ‐ 1:50 Enhancing NMR's Sensitivity by Photochemically-Enhanced Dynamic
Nuclear Polarization Silvia Cavagnero (University of Wisconsin Madison)
1:50 ‐ 2:10 NMR Studies of Substrate Conformation Upon Binding the Hsp70
Chaperone Protein Nese Kurt Yilmaz (University of Wisconsin Madison)
2:10 ‐ 3:10 Keynote Lecture: New Assignment Strategies for Large and Glycosylated
Proteins James H. Prestegard (University of Georgia)
3:10 Coffee
Chair: John Grutzner (Purdue University)
3:30 ‐ 3:50 Chemical Shift Perturbations Reveal Disrupted "Hot Spot" Binding in the
Src SH2 Domain Joshua Ward (Purdue University)
3:50 ‐ 4:10 Application of REDOR SSNMR to Understand Early Steps in HIV Infection
Kelly Sackett (Michigan State University)
4:10 ‐ 4:30 Cu2+ Binding Studies to Alzheimer s B Amyloid Fibrils by Solid state
Alzheimer’s B-Amyloid Solid-state
NMR Sudhakar Parthasarathy (University of Illinois Chicago)
4:30 ‐ 4:50 Magic-Angle Spinning Solid-state NMR Studies of a 41 kDa DsbA-DsbB
Membrane Protein Complex Lindsay Sperling (University of Illinois Urbana-
Champaign)
4:50 ‐ 5:10 Proton Detection Methods for Rapid Structural Analysis of Membrane
Proteins and Fibrils Chad Nieuwkoop (University of Illinois Urbana-
Champaign)
5:10 ‐ 5:30 Chemical Shift Assignments of Alpha-Synuclein Fibrils
Gemma Comellas (University of Illinois Urbana-Champaign)

Monday, October 05, 2009

The Institute Of Cancer Research

(University of London)

Sutton, Surrey, UK

The Section of Magnetic Resonance

The Cancer Research UK and EPSRC Centre for Cancer Imaging

Team Leader - Novel Biomarkers and Probes

Project Leader (Staff Scientist)

Magnetic Resonance in Translational Cancer Research

The Institute of Cancer Research (a College of the University of London) is a world-class cancer research organization with nationally leading HEFCE RAE ratings. In partnership with The Royal Marsden NHS Foundation Trust, we form the largest comprehensive cancer centre in Europe, dedicated to research that extends from epidemiology, genetics and molecular biology, through drug discovery and development, to cancer diagnosis and patient treatment. This makes us uniquely placed to work towards our vision that people may live their lives free from the fear of cancer as a life threatening disease.

The Cancer Research UK and EPSRC Centre for Cancer Imaging focuses on translating preclinical applications of magnetic resonance and other imaging techniques to clinical tools for detection, diagnosis and assessment of cancer and combines expertise from scientists and clinicians based at both the Institute of Cancer Research and Royal Marsden NHS Foundation Trust. Both posts are concerned with developing our programme in 3 areas: identifying MR biomarkers of cancer response to novel therapeutics, developing applications of hyperpolarization in cancer, and developing novel imaging probes and approaches to recognize and report on cellular processes important in cancer. There are excellent opportunities to collaborate with other Sections in the Institute, including the CR-UK Centre for Cancer Therapeutics.

Team Leader

As a Team Leader you will take responsibility for developing aspects of our Cancer Research UK funded programme, and will be expected to develop and lead new research in the areas outlined above. The candidate will have a strong record and post doctoral experience in biochemistry and in MR techniques, with their application to cellular and preclinical models. Team leaders are expected to win substantial competitive grants, publish extensively, supervise PhD students and contribute to all areas of the Section’s academic function.

The post will be at Career Development Faculty level (i.e. tenure track) with a starting salary from £42,230 p.a. to £46,964 p.a. Job no. A326

Project Leader (Staff Scientist)

As a Staff Scientist you will bring skills relevant to the research programme, taking responsibility for projects within our programme, and equipment in the Group. A PhD in an appropriate discipline (biological, physical, chemical, physiological science), significant post doctoral experience, an ability to co-ordinate, plan and execute research and routine studies to a high standard and advanced knowledge of NMR are therefore essential.

Appointment will be to the Staff Scientist scale, depending on skills and experience, (from £37,477 p.a. to £44,336 p.a.). Job no. A325

To discuss the posts further you may contact Professor Martin Leach on +44 (0)20 8661 3338 (martin.leach@icr.ac.uk).

Both posts benefit from generous annual leave entitlements and a final salary pension scheme.

For a full job description, person specification and details of how to apply please see our website at http://www.icr.ac.uk/jobs/current_vacancies/index.shtml or phone our recruitment line on +44 (0)20 7153 5475.

Closing date: 30th October 2009

Monday, September 21, 2009

AAAS Science & Technology Policy Fellowships

Plug the Power of Science into Public Policy

http://fellowships.aaas.org/

The Fellowships help to establish and nurture critical links between federal decision-makers and scientific professionals to support public policy that benefits the wellbeing of the nation and the planet. The Fellowships are designed to:

  • educate scientists and engineers on the intricacies of federal policymaking;
  • provide scientific expertise and analysis to support decision-makers confronting increasingly complex scientific and technical issues;
  • foster positive exchange between scientists and policymakers;
  • empower scientists and engineers to conduct policy-relevant research and other activities that address challenges facing society; and
  • increase the involvement and visibility of scientists and engineers in the public policy realm.

The Fellowships support the AAAS objectives to improve public policymaking through the infusion of science, and to increase public understanding of science and technology and are part of AAAS Science & Policy Programs.

Tuesday, September 01, 2009

Joint EUROMAR 2010 and 17th ISMAR Conference
a World Wide Magnetic Resonance Conference (WWMR2010)
Florence, Italy
July 4-9, 2010
http://www.cerm.unifi.it/wwmr2010

Dear Colleague,

It is a pleasure to invite you to attend the Joint EUROMAR 2010 and 17th
ISMAR Conference, a World Wide Magnetic Resonance Conference (WWMR2010),
that will be held in Florence (Italy) July 4-9, 2010.

There are many good reasons for attending WWMR2010!

You will be able to take advantage of a truly international arena for
presenting the results of your studies, as well as to learn about the
most advanced achievements of basic and applied research in the magnetic
resonance field.

You will also have the opportunity to meet colleagues from countries
throughout the world for fruitful discussion and planning of joint
research initiatives.

The unique artistic and cultural heritage of Florence will provide an
unforgettable scenario...

The Conference program includes plenary talks by Lyndon Emsley, Clare P.
Grey, Christian Griesinger, Robert G. Griffin, Sarah J. Nelson, Hitoshi
Ohta, Daniel Rugar, and Frances Separovic. The list of the invited
speakers is increasing and it is continuously updated on the Conference
website.

Don't forget to save the dates in your agenda!

Registration and abstract submission will be opened soon. Please visit
and bookmark the conference website at

www.cerm.unifi.it/wwmr2010
, which
is being continuously updated!

We look forward to welcoming you in Florence.

Arrivederci!

Ivano Bertini
Chair of WWMR2010

Roberta Pierattelli
WWMR2010 Advertising Committee

**************************************************
Joint EUROMAR 2010 and 17th ISMAR Conference
Florence (Italy), July 4-9, 2010

c/o Magnetic Resonance Center - CERM
University of Florence
Via L. Sacconi 6, 50019 Sesto Fiorentino (Florence)
ITALY

http://www.cerm.unifi.it/wwmr2010
tel: + 390554574296
fax: + 390554574271
skype: wwmr2010

Friday, August 28, 2009

Imaging 2020 VI: Imaging Biopathways
September 13-17, 2009

Jackson Hole, Wyoming

imagingin2010.com

Future medical therapies will increasingly focus on interrupting and redirecting pathologic biopathways at the genetic and cellular level. Imaging – especially molecular imaging - will play an indispensible role in the understanding of biopathways, the creation of biospecific interventions, and the monitoring and control of new, highly potent interventions.

Future imaging will require significantly greater sensitivity, specificity and quantitative robustness than exists today. The most significant evolution and greatest challenge will be increasing the specificity. To fully integrate imaging into therapeutics and diagnosis, imaging will need to be applicable to screening and interrogating therapeutically useful biopathways. Sessions have been designed around these themes. Discussions will address future advances in engineering and imaging modalities from NIR to X ray, microscopic in vivo imaging, fundamental advances in important biopathways (angiogenesis, metastasis, invasion and resistance, neurodegeneration, et al.), and the future roles of chemistry in imaging.

Key to meeting the challenges inherent in a complex future is open and effective communication among basic and clinical researchers from a wide spectrum of relevant disciplines. The goal of Imaging in 2020 is to catalyze this communication by laying the technical foundation for it, and by providing a format that is intentionally less structured than the traditional scientific meeting, allowing for extensive, meaningful interactions in a casual, comfortable environment. We hope to foster the development of enduring associations that will lead to innovative solutions and applications.

Imaging in 2020 VI will be held at the Jackson Lake Lodge in
Jackson Hole, Wyoming. Its beautiful location in Grand Teton National Forest is easily accessible from Jackson Airport. Breathtaking views of the Grand Tetons provide a colorful backdrop to the meeting. Participants will have the opportunity during the unscheduled afternoons to enjoy a variety of outdoor activities, such as hiking, fishing, boating, horseback riding, or just relaxing in a truly spectacular natural setting.

Sunday, September 13
4:00 - 6:00 pm Registration and Poster Set-up
6:00 - 7:00 pm Dinner
7:00 - 7:15 pm Welcome Mike Tweedle
7:15 - 9:00 pm Session I: Engineering
7:15 - 7:30 pm Session Remarks (1999) Tom Budinger (Moderator)
7:30 - 8:15 pm Hardware, Miniaturization, Microfluidics Greg Auner
8:15 - 9:00 pm The Future of Today's Modalities John Gore
9:00 - 10:00 pm Reception and Poster Session



Monday, September 14
7:00 - 8:00 am Breakfast
8:00 - 9:45 am Session II: Chemistry I

8:00 - 8:15 am Session Remarks (1999) Mike Tweedle (Moderator)
8:15 - 9:00 am Supramolecular Chemistry Akira Harada
9:00 - 9:45 am Multimodality Imaging Agents Angelique Louie
9:45 - 10:00 am Break
10:00 - 12:15 pm
Session III: Biopathways I

10:00 - 10:45 am Session Remarks/Angiogenesis Pathology Don McDonald
10:45 - 11:30 am MRI Angiogenesis Michal Neeman
11:30 - 12:15 pm PET Angiogenesis Markus Schwaiger
12:15 - 1:15 pm Lunch
1:15 - 6:00 pm Afternoon free time
6:00 - 7:00 pm Dinner
7:15 - 8:45 pm Session IV: Biopathways II
7:00 - 7:15 pm Session Remarks (2003) Adrian Nunn (Moderator)
7:15 - 8:00 pm Metatases & Cell Motility John Condeelis
8:00 - 8:45 pm Cancer Invasion and Resistance Peter Friedl
8:45 - 10:00 pm Reception and Poster Session



Tuesday, September 15
7:00 - 8:00 am Breakfast
8:00 - 9:45 am Session V: Chemistry II

8:00 - 8:15 am Session Remarks (1999) Tom Meade (Moderator)
8:15 - 9:00 am Topic TBD Brian Hoffman
9:00 - 9:45 am Topic TBD Ken Raymond
9:45 - 10:15 am Group Photo, Break
10:15 - 12:00 pm Session VI: Pharmaceuticals
10:15 - 10:30 am Session Remarks Bradford Navia (Moderator)
10:30 - 11:15 am Neurodegenerative Disease Dan Silverman
11:15 - 12:00 pm Imaging Biomarkers in Cancer Michael Smith
12:00 - 12:45 pm Lunch
12:45 - 6:00 pm Afternoon free time/Bus trip into Jackson Hole

6:00 - 6:45 pm Reception
6:45 - 7:45 pm
Dinner
7:45 - 7:55 pm
Introduction of Keynote Speaker
Bonnie Sloane
7:55 - 8:55 pm
Keynote Address
Roger Tsien
2008 Nobel Prizewinner for Chemistry



Wednesday, September 16
7:00 - 8:00 am Breakfast
8:00 - 9:45 am Sessoin VII: Ultrasound Agents
8:00 - 8:15 am Session Remarks (1999) Kathy Ferrara (Moderator)
8:15 - 9:00 am Targeted Ultrasound Agents Sasha Klibanov
9:00 - 9:45 am Advances in Technology for Ultrasound Contrast Imaging Paul Dayton
9:45 - 10:00 am Break
10:00 - 11:45 am Session VIII: Microscopy
10:00 - 10:15 am Session Remarks Bob Gillies (Moderator)
10:15 - 11:00 am Endoscopic Microscopy Rebecca Richards-Kortum
11:00 - 11:45 am Microscopy with Gallium Ions Sriram Subramaniam
11:45 - 12:30 pm Lunch
12:45 - 6:00 pm Afternoon free time
6:00 - 7:00 pm Dinner
7:00 - 8:45 pm Session IX: Animal Models
7:00 - 7:15 pm Session Remarks (1999) Dan Sullivan (Moderator)
7:15 - 8:00 pm Animal Model Development Terry Van Dyke
8:00 - 8:45 pm Animal Models for Optical Imaging David Kirsch
8:45 - 10:00 pm Reception and Poster Session



Thursday, September 17
7:00 - 8:00 am Breakfast
8:00 - 10:15 am Session X: Imaging Biologicals

8:00 - 8:15 am Session Remarks Sarah Nelson (Moderator)
8:15 - 9:00 am Cell Imaging In Vivo Joe Frank
9:00 - 9:45 am Imaging Enzymes Matthew Bogyo
9:45 - 10:15 am Meeting Summary & Concluding Remarks Bonnie Sloane, Mike Tweedle