Saturday, September 01, 2012

Autism Brain Imaging Data Exchange (ABIDE) Sample

 
 
The International Neuroimaging Data-Sharing Initiative (INDI), in coordination with the Child Mind Institute, announces the public release of the "Autism Brain Imaging Data Exchange (ABIDE) Sample" via the 1000 Functional Connectomes Project (http://fcon_1000.projects.nitrc.org/indi/abide/index.html).
 
Drs. Adriana Di Martino (NYU Child Study Center; consortium coordinator) and Stewart Mostofsky (Kennedy Krieger Institute) have assembled ABIDE as an international consortium explicitly dedicated to the sharing of previously collected resting state functional magnetic resonance imaging (R-fMRI) and morphometric data for autism. To date, the effort has brought together 20 samples from 16 contributing sites, yielding an aggregate dataset of 539 individuals with autism and 573 typical controls. The effort builds upon the model of the highly successful ADHD-200 Consortium (http://fcon_1000.projects.nitrc.org/indi/adhd200/), though providing an extensive array of phenotypic characterizations common to nearly all sites, that far exceeds it predecessor. Key diagnostic and assessment schedules (e.g., ADOS, ADIS), psychometric testing (e.g., IQ) and a variety of additional questionnaires, commonly employed in the autism community, are being shared along with brain imaging data.
 
In addition to distributing ABIDE datasets in .tar and .csv file formats via NITRC as is customary for the FCP, the INDI team has recruited the efforts of leading informatics platforms including COINS: http://coins.mrn.org; LORIS: http://cbrain.mcgill.ca/loris; LONI IDA: http://pipeline.loni.ucla.edu/; NITRC-IR/XNAT: http://www.nitrc.org/ir. They have each agreed to host the ABIDE datasets prepared by the INDI team. Such coordination is intended to give users an opportunity to sample emerging technologies and explore the value of these platforms not only for sharing, but also for their own internal infrastructure.